| Career Pitching | |||||||||||||||||||
| Thru 2024 | |||||||||||||||||||
| Innings Pitched | |||||||||||||||||||
| Name | GP | GS | CG | ShO | GF | W | L | Sv | IP | ER | H | SO | BB | ERA | OBA* | WHIP | SO/9 | BB/9 | H/9 |
| Clemens, Roger | 629 | 629 | 210 | 25 | 0 | 285 | 219 | 0 | 4500.2 | 1922 | 3593 | 4336 | 1683 | 3.84 | .210 | 1.17 | 8.67 | 3.37 | 7.18 |
| Maddux, Greg | 655 | 622 | 214 | 25 | 18 | 298 | 181 | 0 | 4495.1 | 1952 | 3840 | 3084 | 1135 | 3.91 | .222 | 1.11 | 6.17 | 2.27 | 7.69 |
| Johnson, Randy | 474 | 466 | 135 | 15 | 3 | 194 | 185 | 0 | 3293.2 | 1535 | 2694 | 3312 | 1288 | 4.19 | .214 | 1.21 | 9.05 | 3.52 | 7.36 |
| Glavine, Tom | 539 | 488 | 80 | 17 | 19 | 170 | 169 | 0 | 3282 | 1765 | 3028 | 2100 | 1381 | 4.84 | .235 | 1.34 | 5.76 | 3.79 | 8.30 |
| Mussina, Mike | 444 | 442 | 99 | 23 | 1 | 204 | 129 | 0 | 3017 | 1491 | 2739 | 2316 | 1070 | 4.45 | .232 | 1.26 | 6.91 | 3.19 | 8.17 |
| Greinke, Zack | 480 | 422 | 59 | 20 | 12 | 191 | 136 | 3 | 2797.2 | 1266 | 2318 | 2452 | 904 | 4.07 | .216 | 1.15 | 7.89 | 2.91 | 7.46 |
| Verlander, Justin | 441 | 430 | 58 | 20 | 0 | 182 | 128 | 0 | 2791 | 1208 | 2170 | 2742 | 945 | 3.90 | .206 | 1.12 | 8.84 | 3.05 | 7.00 |
| Smoltz, John | 570 | 381 | 58 | 15 | 90 | 161 | 159 | 17 | 2708 | 1339 | 2426 | 2290 | 1003 | 4.45 | .230 | 1.27 | 7.61 | 3.33 | 8.06 |
| Hudson, Tim | 450 | 401 | 51 | 14 | 16 | 162 | 119 | 0 | 2670.2 | 1158 | 2256 | 1763 | 952 | 3.90 | .220 | 1.20 | 5.94 | 3.21 | 7.60 |
| Kershaw, Clayton | 411 | 410 | 80 | 15 | 0 | 177 | 152 | 0 | 2661 | 1122 | 1916 | 2693 | 888 | 3.79 | .194 | 1.05 | 9.11 | 3.00 | 6.48 |
| Schilling, Curt | 431 | 382 | 74 | 8 | 35 | 173 | 109 | 0 | 2658 | 1253 | 2460 | 2271 | 807 | 4.24 | .236 | 1.23 | 7.69 | 2.73 | 8.33 |
| Moyer, Jamie | 415 | 410 | 83 | 16 | 5 | 157 | 145 | 0 | 2628.2 | 1276 | 2333 | 1652 | 885 | 4.37 | .228 | 1.22 | 5.66 | 3.03 | 7.99 |
| Martinez, Pedro J. | 404 | 343 | 90 | 4 | 42 | 143 | 139 | 11 | 2519.1 | 1255 | 2080 | 2487 | 965 | 4.48 | .216 | 1.21 | 8.88 | 3.45 | 7.43 |
| Hershiser, Orel | 389 | 387 | 79 | 7 | 1 | 143 | 144 | 0 | 2463.2 | 1153 | 2055 | 1615 | 824 | 4.21 | .218 | 1.17 | 5.90 | 3.01 | 7.51 |
| Brown, Kevin | 330 | 326 | 135 | 23 | 3 | 154 | 135 | 0 | 2441.1 | 1041 | 1904 | 2014 | 849 | 3.84 | .206 | 1.13 | 7.42 | 3.13 | 7.02 |
| Sabathia, C.C. | 400 | 371 | 58 | 10 | 22 | 147 | 107 | 0 | 2367.1 | 1158 | 2167 | 2021 | 892 | 4.40 | .234 | 1.29 | 7.68 | 3.39 | 8.24 |
| Pettitte, Andy | 356 | 343 | 54 | 10 | 8 | 134 | 119 | 0 | 2268.1 | 1112 | 2020 | 1574 | 801 | 4.41 | .229 | 1.24 | 6.25 | 3.18 | 8.01 |
| Halladay, Roy | 348 | 340 | 71 | 11 | 3 | 155 | 104 | 0 | 2255 | 928 | 1784 | 1660 | 704 | 3.70 | .209 | 1.10 | 6.63 | 2.81 | 7.12 |
| Cone, David | 323 | 323 | 80 | 11 | 0 | 116 | 111 | 0 | 2236 | 1027 | 1874 | 1902 | 885 | 4.13 | .218 | 1.23 | 7.66 | 3.56 | 7.54 |
| Buehrle, Mark | 426 | 308 | 40 | 5 | 76 | 84 | 132 | 0 | 2211.2 | 1196 | 2169 | 1361 | 746 | 4.87 | .246 | 1.32 | 5.54 | 3.04 | 8.83 |
| Scherzer, Max | 372 | 328 | 26 | 5 | 35 | 139 | 109 | 7 | 2207.1 | 945 | 1713 | 2505 | 720 | 3.85 | .206 | 1.10 | 10.21 | 2.94 | 6.98 |
| Wells, David | 375 | 323 | 83 | 7 | 1 | 113 | 127 | 20 | 2169 | 1091 | 2106 | 1486 | 564 | 4.53 | .245 | 1.23 | 6.17 | 2.34 | 8.74 |
| Hamels, Cole | 348 | 321 | 39 | 13 | 20 | 129 | 101 | 1 | 2102.2 | 903 | 1799 | 1950 | 699 | 3.87 | .222 | 1.19 | 8.35 | 2.99 | 7.70 |
| Appier, Kevin | 321 | 319 | 57 | 10 | 2 | 117 | 113 | 0 | 2102.1 | 1081 | 1851 | 1663 | 896 | 4.63 | .227 | 1.31 | 7.12 | 3.84 | 7.92 |
| Saberhagen, Bret | 318 | 313 | 90 | 7 | 1 | 118 | 128 | 0 | 2096.2 | 1043 | 1915 | 1386 | 590 | 4.48 | .233 | 1.19 | 5.95 | 2.53 | 8.22 |
| Hernandez, Felix | 334 | 319 | 35 | 6 | 7 | 113 | 116 | 0 | 2094.1 | 948 | 1716 | 1884 | 796 | 4.07 | .215 | 1.20 | 8.10 | 3.42 | 7.37 |
| Martinez, Dennis | 319 | 315 | 55 | 10 | 3 | 128 | 99 | 0 | 2053 | 965 | 1518 | 1155 | 650 | 4.23 | .198 | 1.06 | 5.06 | 2.85 | 6.65 |
| Ryan, Nolan | 298 | 298 | 78 | 8 | 0 | 119 | 113 | 0 | 2052 | 990 | 1107 | 1760 | 780 | 4.34 | .152 | 0.92 | 7.72 | 3.42 | 4.86 |
| Rogers, Kenny | 398 | 291 | 51 | 7 | 26 | 107 | 106 | 0 | 2026.1 | 1109 | 1949 | 1261 | 766 | 4.93 | .243 | 1.34 | 5.60 | 3.40 | 8.66 |